Wnt4 coordinates directional cell migration and extension.
Cell Matrix was founded in 1999 by Nicholas Macias. The company is located in Blacksburg, Virginia, U.S.A. with satellite operations in Portland, Oregon, U.S.A. Technology: Cell Matrix develops complete systems: hardware, logic, circuits, low-level software, algorithms, high-level software and programming interfaces, and user interfaces. Many Cell Matrix solutions exploit a fine-grained.
In February 2016, the average time from submission to first decision for all original research papers submitted to Circulation Research was 15.4 days. Current address for G. D’Amico: Adhesion and Angiogenesis Laboratory, Centre for Tumor Biology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
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Tissue, organ and organoid cultures provide suitable models for developmental studies, but our understanding of how the organs are assembled at the single-cell level still remains unclear. We describe here a novel fixed z -direction (FiZD) culture setup that permits high-resolution confocal imaging of organoids and embryonic tissues. In a FiZD culture a permeable membrane compresses the.
The small GTPase RhoA is a major regulator of actin reorganization during the formation of stress fibers; thus identifying molecules that regulate Rho activity is necessary for a complete understanding of the mechanisms that determine cell contractility. Here, we have identified Arhgap28 as a Rho GTPase activating protein (RhoGAP) that switches RhoA to its inactive form.
Background Formation of apical compartments underlies the morphogenesis of most epithelial organs during development. The extracellular matrix (ECM), particularly the basement membrane (BM), plays an important role in orienting the apico-basal polarity and thereby the positioning of apical lumens. Integrins have been recognized as essential mediators of matrix-derived polarity signals. The.